Chemical Dependency Counselor Practice Exam 2025 - Free Practice Questions and Study Guide

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Which medication combines properties of both agonist and antagonist in treating opiate addiction?

Naltrexone

Buprenorphine

Buprenorphine is considered a partial agonist at mu-opioid receptors, which means it activates these receptors but does so to a lesser degree than full agonists like morphine or methadone. This partial agonist property allows buprenorphine to alleviate withdrawal symptoms and cravings in individuals with opiate addiction while simultaneously reducing the risk of misuse because it does not produce the same euphoric effects associated with full agonists. Additionally, buprenorphine has antagonist properties as it can block the effects of other opioids when taken in higher doses. This unique combination of properties makes buprenorphine an effective treatment option in managing opiate dependence, offering a balance between mitigating withdrawal while minimizing the potential for abuse.

The other medications listed do not possess both agonist and antagonist qualities for treating opiate addiction in the same manner. For example, naltrexone is a full antagonist of opioid receptors and is effective in preventing relapse but does not alleviate withdrawal symptoms, making it unsuitable for initial treatment in addiction. Acamprosate and disulfiram are utilized for alcohol dependence and do not interact with opioid receptors in the context of opioid addiction treatment.

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Acamprosate

Disulfiram

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